Lindsay Lohan stars as Cady Heron, a teenage girl who has been home-schooled in the African bush country her entire life. Having just returned from Africa, she is new to the confusing cultural mish-mash of contemporary high school, where the law of the jungle takes on a whole new meaning. Still, she manages to get along fairly well until she falls for the ex-boyfriend of Regina (Rachel McAdams), the leader of Cady's A-list clique. Written by co-star Tina Fey, the comedy also features Amanda Seyfried, as well as Amy Poehler, Ana Gasteyer and Tim Meadows of "Saturday Night Live" fame. Directed by Mark Waters (The Spiderwick Chronicles, Freaky Friday).