The last day Portland slacker John Callahan (Joaquin Phoenix) is able to walk, he wakes up without a hangover—because he’s still drunk from the night before. That night at a wild party he meets a wisecracking drinking buddy (Jack Black), who insists they leave for an even better party he knows about. But when his new friend dozes off at the wheel, John wakes up confined to a wheelchair with only partial use of his arms. Though he initially has no intention of getting sober, he reluctantly attends a 12-step meeting run by a charismatic and dedicated sponsor named Donnie (Jonah Hill) and reconnects with Annu (Rooney Mara), a therapist he met at the hospital. With their encouragement, John finds that love is not beyond his reach and discovers a hidden talent for drawing, channeling his playful personality into crude, politically incorrect—and often hilarious—cartoons, which develop a national following. Based on a true story, this poignant, insightful, funny drama about redemption, forgiveness and the healing power of art is adapted from Callahan’s autobiography and directed by two-time Oscar nominee Gus Van Sant (Milk, Good Will Hunting).